• 林秋宁

    研究员,博士生导师,国家自然科学基金优秀青年基金获得者。

    2007获得华东理工大学学士学位,2013年获华东理工大学博士学位,同年留校从事博士后研究工作。2016-2017年赴美国华盛顿州立大学访问一年,20178月回国任华东理工大学副研究员,2020年初加入yd12300云顶线路。2020年获中国生物医学工程学会青年学者奖、唐仲英基金会“仲英青年学者”称号,并获国家自然科学基金优秀青年科学基金资助。一直从事生物医用材料的基础和应用研究,创新性提出光化学偶联反应构建水凝胶的新方法和近红外光控制药物释放的新手段。在Nat. Mater.Sci. Adv.Adv. Mater.J. Am. Chem. Soc.Angew. Chem.等国际重要学术期刊上发表论文60余篇,研究工作获得哈佛医学院、麻省理工学院、美国NIH等生物材料及医学领域相关知名研究组的高度评价。申/获中国及国际PCT专利20余项,授权14项,所建立的方法在生物医药领域具有重要的临床转化价值,已实现1项技术转化。主持/参与国家自然科学基金、国家重点研发计划、上海市人才计划等项目。

研究方向

1)水凝胶生物材料

2)光智能生物材料

3)生物3D制造

4)药物控释

代表性论文专著

1.      B.-K Bao, Q.-M Zeng, K. Li, J.-F Wen, Y.-Q Zhang, Y.-J Zheng, R.-J Zhou, C.-T Shi, T. Chen, C.-N Xiao, B.-H Chen, T. Wang, K. Yu, Y. Sun, Q.-N Lin*, Y. He, S.-T Tu, L.-Y Zhu*, Rapid fabrication of physically robust hydrogels, Nat. Mater. 2023, 22, 1253-1260.

2.      Y.-X Fan, T. Liu*, Y.-Z Li, X.-P Miao, B.-H Chen, J. Ding, Z.-X Dong, O. Rios, B.-K Bao, Q.-N Lin*, L.-Y Zhu, One-Step Manufacturing of Supramolecular Liquid-Crystal Elastomers by Stress-Induced Alignment and Hydrogen Bond Exchange, Angew. Chem. Int. Ed. 2023, 62, e202308793.

3.      Y.-J Hua, H.-T Xia, L.-T Jia, J.-Z Zhao, D.-D Zhao, X.-Y Yan, Y.-Q Zhang, S.-J Tang, G.-D Zhou*, L.-Y Zhu, Q.-N Lin*, Ultrafast, tough, and adhesive hydrogel based on hybrid photocrosslinking for articular cartilage repair in water-filled arthroscopy, Sci. Adv. 2021, 7, eabg0628.

4.      W.-J. Zhang, B.-K Bao, F. Jiang, Y.-Q Zhang, R.-J Zhou, Y.-Z Lu, S.-H Lin, Q.-N Lin*, X.-Q Jiang*, L.-Y Zhu*, Promoting Oral Mucosal Wound Healing with a Hydrogel Adhesive Based on a Phototriggered S-Nitrosylation Coupling Reaction, Adv. Mater. 2021, 33, 2105667.

5.      Q.-N. Lin#, L.-P. Yang#, Z.-Q. Wang, Y.-J. Hua, D.-S. Zhang, B.-K. Bao, C.-Y. Bao, X.-Q. Gong, L.-Y. Zhu*, Coumarin Photocages Modified with an Electron-Rich Styryl Moiety at the 3-Position: Long Wavelength Excitation, Rapid Photolysis and Photobleaching, Angew. Chem. Int. Ed., 2018, 57, 3722-3726.

6.      Y.-L. Yang#, J.-Y. Zhang#, Z.-Z. Liu, Q.-N. Lin*, X.-L. Liu, C.-Y. Bao, Y. Wang*, L.-Y. Zhu*, Tissue-Integratable and Biocompatible Photogelation by the Imine Crosslinking Reaction, Adv. Mater., 2016, 28, 2724-2730.

7.      Z.-Z. Liu, T. Liu, Q.-N. Lin*, C.-Y. Bao, L.-Y. Zhu*, Sequential Control over Thiol Click Chemistry by a Reversibly Photoactivated Thiol Mechanism of Spirothiopyran, Angew. Chem. Int. Ed., 2015, 54, 174-178.

8.      Q.-N. Lin, C.-Y. Bao, Y.-L. Yang, Q.-N. Liang, D.-S. Zhang, S.-Y. Cheng, L.-Y. Zhu*, Highly Discriminating Photorelease of Anticancer Drugs Based on Tumor-Hypoxia Activatable Phototriggers Conjugated Chitosan Nanoparticles, Adv. Mater., 2013, 25, 1981-1986.

9.      Q.-N. Lin, C.-Y. Bao, S.-Y. Cheng, Y.-L. Yang, W. Ji, L.-Y. Zhu*, Target-Activated Coumarin Phototriggers Specifically Switch on Fluorescence and Photocleavage upon Bonding to Thiol-Bearing Protein, J. Am. Chem. Soc., 2012, 134, 5052-5055.

10.   Q.-N. Lin, Q. Huang, C.-Y. Li, C.-Y. Bao*, Z.-Z. Liu, F.-Y. Li, L.-Y. Zhu*, Anticancer Drug Release from a Mesoporous Silica Based Nanophotocage Regulated by Either a One- or Two-Photon Process, J. Am. Chem. Soc., 2010, 132, 10645-10647.

联系方式

邮箱地址:qiuninglin@sjtu.edu.cn

办公地址:闵行校区文选医学楼513室